Biologics
Pharmaceuticals

Regeneron's trevogrumab preserves muscle during semaglutide weight loss

Phase 2 COURAGE trial data, published in The Lancet, show trevogrumab preserved up to 70% of muscle loss caused by semaglutide in obesity patients.
Phase 2 COURAGE trial data, published in The Lancet, show trevogrumab preserved up to 70% of muscle loss caused by semaglutide in obesity patients.
Pharmaceuticals
Biologics

Survodutide hits 13.1% weight loss in Phase III obesity-T2D trial

Boehringer Ingelheim's glucagon/GLP-1 dual agonist met both co-primary endpoints in SYNCHRONIZE-2, with full results published simultaneously in the New England
Boehringer Ingelheim's glucagon/GLP-1 dual agonist met both co-primary endpoints in SYNCHRONIZE-2, with full results published simultaneously in the New England
Biologics
Pharmaceuticals

Egle Therapeutics: EGL-003 Phase 1 shows clean safety, Treg lift

Egle's IL-2 agonist EGL-003 was well tolerated across four dose cohorts and produced selective Treg expansion, supporting a Q4 2026 atopic dermatitis
Egle's IL-2 agonist EGL-003 was well tolerated across four dose cohorts and produced selective Treg expansion, supporting a Q4 2026 atopic dermatitis
Medical Devices
Bioprocessing

Integer Holdings clears US antitrust hurdle in $5.7bn KKR buyout

Integer Holdings has received early HSR termination for its $5.7bn acquisition by KKR, with a stockholder vote scheduled for 21 October 2026.
Integer Holdings has received early HSR termination for its $5.7bn acquisition by KKR, with a stockholder vote scheduled for 21 October 2026.
Pharmaceuticals
Biologics

Highlight Therapeutics: BO-112 meets Phase 2b BCC endpoint

Highlight Therapeutics' intralesional BO-112 met its primary visual and pathological response endpoint in 61% of basal cell carcinoma patients.
Highlight Therapeutics' intralesional BO-112 met its primary visual and pathological response endpoint in 61% of basal cell carcinoma patients.
Cell & Gene Therapy
Biologics
Genomics

Atsena's ATSN-201 shows durable XLRS benefit at 18 months

Atsena Therapeutics reported sustained structural and functional gains in seven of nine treated eyes, with a BLA filing now targeted for late 2028.
Atsena Therapeutics reported sustained structural and functional gains in seven of nine treated eyes, with a BLA filing now targeted for late 2028.
Biologics
Pharmaceuticals

Connect Biopharma: rademikibart cuts COPD failure rate 81% in Ph2

Connect Biopharma's IL-4Rα antibody rademikibart met its primary endpoint in a Phase 2 COPD trial, eliminating hospital return visits versus placebo.
Connect Biopharma's IL-4Rα antibody rademikibart met its primary endpoint in a Phase 2 COPD trial, eliminating hospital return visits versus placebo.
Biologics
Cell & Gene Therapy

Candel reports durable immune remodelling data for aglatimagene

AI-enabled digital pathology shows aglatimagene drove sustained lymphocyte-tumour engagement more than two years after treatment in a phase 3 prostate cancer trial.
AI-enabled digital pathology shows aglatimagene drove sustained lymphocyte-tumour engagement more than two years after treatment in a phase 3 prostate cancer trial.
Medical Devices
Digital Health
Diagnostics

Ceribell wins FDA clearance for qEEG trending on its AI platform

Ceribell's 510(k)-cleared software adds three quantitative EEG tools to its point-of-care platform, covering patients from premature neonates to adult ICU
Ceribell's 510(k)-cleared software adds three quantitative EEG tools to its point-of-care platform, covering patients from premature neonates to adult ICU
Cell & Gene Therapy
Bioprocessing
Biologics

MiNK Therapeutics joins ARPA-H BoSS room-temperature cell therapy push

MiNK's iNKT platform joins an $87 million ARPA-H programme seeking to eliminate cold-chain dependence in allogeneic cell therapy distribution.
MiNK's iNKT platform joins an $87 million ARPA-H programme seeking to eliminate cold-chain dependence in allogeneic cell therapy distribution.
Pharmaceuticals
Biologics

Novo Nordisk CagriSema data shows brain, organ and bone effects

New EASD 2026 data show CagriSema modifies brain food-cue responses and reduces ectopic fat, with bone health maintained during weight loss.
New EASD 2026 data show CagriSema modifies brain food-cue responses and reduces ectopic fat, with bone health maintained during weight loss.
Pharmaceuticals

Moleculin Biotech completes Part A enrolment in AML MIRACLE trial

Moleculin has closed enrolment of 89 subjects in Part A of its pivotal MIRACLE trial, targeting a comprehensive data readout in Q1 2027.
Moleculin has closed enrolment of 89 subjects in Part A of its pivotal MIRACLE trial, targeting a comprehensive data readout in Q1 2027.
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